Transgenic animals

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Transgenic animals

The technique of introducing new genetic material into the germline of mammals has been a major development in biotechnology over the last decades. ”Transgenic animals“ are animals whose chromosomes contain stable, integrated copies of exogenous genes, additional copies of endogenous genes or gene constructs. They are frequently created by two different techniques: microinjection of DNA into th...

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Transgenic Animals

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Transgenic Animals

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Transgenic Animals

The term transgenic animal refers to an animal in which there has been a deliberate modification of the genome the material responsible for inherited characteristics in contrast to spontaneous mutation (FELASA September 1992, revised February 1995). Foreign DNA is introduced into the animal, using recombinant DNA technology, and then must be transmitted through the germ line so that every cell,...

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Transgenic animals and gonadotrophins.

A variety of transgenic animal models has been developed to elucidate in vivo the functions of gonadotrophin genes. Some of these have focused on regulatory aspects through expression of gonadotrophin subunit promoter-driven reporter genes. Others have been carried out by overexpression or targeted disruption of specific gonadotrophin subunit genes, or by eliminating pituitary gonadotroph cells...

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ژورنال

عنوان ژورنال: Journal of Medical Genetics

سال: 1993

ISSN: 1468-6244

DOI: 10.1136/jmg.30.7.623